Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1159H1760N264O349S9

DescriptionStandard

        IDDLAEVDYALNSLPAVFRPFIDLDLKGIVYPSGNYTGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAEYSVTPYPVMLKLMATEIPVISLEQDSFTVEIRGSMEVFAVLPDSATQSLFTMNITANTSIAPNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENIMSYILQTEVLPSANGKAAFQSISLK
    

Molecular Weight25264.52 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-16.14

Net Charge (pH 7.4) -16.48

Charge Density (pH 7.0) -0.0705

GRAVY Index0.32

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index50.83

Aliphatic Index 96.72

Aromaticity 0.1310

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321497 VERIFIED: NO

Provenance & Taxonomy

OrganismBaryphthengus martii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria