Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC544H878N148O167S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIYVTAVELPSASISLRPGSGIKLVIGNASLTIDMSWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNSSPTSISLTSCRTTSGDVDIKLNGKT
    

Molecular Weight12259.88 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)4.13

Net Charge (pH 7.4) 3.93

Charge Density (pH 7.0) 0.0362

GRAVY Index-0.01

Hydrophobic Moment 0.54

Boman Index0.09

Instability Index30.42

Aliphatic Index 92.28

Aromaticity 0.0702

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5046.89

LogP -58.63

H-bond Donors 182.0

H-bond Acceptors 176.0

Rotatable Bonds 404.0

Heavy Atoms 862.0

Ring Count 17.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126678 VERIFIED: NO

Provenance & Taxonomy

OrganismDicaeum eximium [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria