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MYP_159132
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C39H66N10O9
Standard
Sequence
FQKVVAK
Physicochemical Analysis
819.00 Da
10.00
1.76
1.55
0.2512
0.24
0.65
0.02
-3.56
97.14
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
333.05
-1.59
11.0
11.0
28.0
58.0
1.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0075829 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0114640 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
2.1
IC50
PaperMito K., Fujii M., Kuwahara M., Matsumura N., Shimizu T., Sugano S., Karaki H.. Antihypertensive effect of angiotensin I-converting enzyme inhibitory peptides derived from hemoglobin. Eur. J. Pharmacol., 304, 93-98.
RECORD: Rec_0153211 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antihypertensive
RECORD: Rec_0153981 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0235150 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
2.1 μM
IC50
PaperAntihypertensive effect of angiotensin I-converting enzyme inhibitory peptides derived from hemoglobin PMID8813589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8813589/
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