Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC446H701N133O124S12

DescriptionStandard

        MCIWKPEKLYSKMHNSSIIFEKTQYETEEKNTARGKEHHAVFNMWDACIKLRGQCKKHCGENEYRIAYCARHTVHCCMKRCKPVEK
    

Molecular Weight10294.93 Da

Isoelectric Point (pI)9.07

Net Charge (pH 7.0)6.95

Net Charge (pH 7.4) 6.28

Charge Density (pH 7.0) 0.0809

GRAVY Index-0.89

Hydrophobic Moment 0.51

Boman Index-0.22

Instability Index36.02

Aliphatic Index 47.67

Aromaticity 0.0930

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4198.71

LogP -38.47

H-bond Donors 155.0

H-bond Acceptors 149.0

Rotatable Bonds 352.0

Heavy Atoms 715.0

Ring Count 18.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103675 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence