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MYP_159077
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Basic Information
peptide from aS1-casein
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid agonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Standard
6 amino acids
C43H54N6O11
Standard
Sequence
YFYPEL
Physicochemical Analysis
830.92 Da
4.05
-1.24
-1.45
-0.2065
-0.18
0.32
0.36
112.20
65.00
0.5000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
277.79
1.38
9.0
10.0
21.0
60.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0249994 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperDe Gobba C., Tompa G., Otte J.. Bioactive peptides from caseins released by cold active proteolytic enzymes from Arsukibacterium ikkense. Food Chemistry 165, 205-215. PMID25038668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25038668/
RECORD: Rec_0272550 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand Mucin secretagogue Opioid agonist
HT29-MTX cells
PaperNovel peptides derived from αs1-casein with opioid activity and mucin stimulatory effect on HT29-MTX cells | Fernandez-Tome, S. et al. | DOI: 10.1016/j.jff.2016.06.023 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0290873 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0291231 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Superoxide scavenging
79.2 μM
IC50
PaperIsolation and characterization of free radical scavenging activities peptides derived from casein | Suetsuna, K. et al. | DOI: 10.1016/s0955-2863(99)00083-2 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0342109 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Macrophage-modulating
Caco-2 cells
79.2 μM
IC50
PaperIn Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides | Amigo, L. et al. | DOI: 10.3390/foods9080991 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
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