Peptide Database

Peptide NameDelta lysin I

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC124H203N29O35S

DescriptionStandard

        MAADIISTIGDLVKWIIDTVNKFK
    

Molecular Weight2692.18 Da

Isoelectric Point (pI)5.79

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0208

GRAVY Index0.57

Hydrophobic Moment 0.68

Boman Index0.26

Instability Index7.33

Aliphatic Index 130.00

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1042.15

LogP -6.03

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 91.0

Heavy Atoms 189.0

Ring Count 3.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106168 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli Top10

Activity60 μM

MethodMIC

RECORD: Rec_0260476 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus epidermidis [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)