Peptide Database

Peptide NameCathelicidin-1 (CATH-1) (Fowlicidin-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC711H1151N199O206S9

DescriptionStandard

        MLSCWVLLLALLGGACALPAPLGYSQALAQAVDSYNQRPEVQNAFRLLSADPEPGPNVQLSSLHNLNFTIMETRCQARSGAQLDSCEFKEDGLVKDCAAPVVLQGGRAVLDVTCVDSMADPVRVKRVWPLVIRTVIAGYNLYRAIKKK
    

Molecular Weight16071.54 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.16

Charge Density (pH 7.0) 0.0104

GRAVY Index0.14

Hydrophobic Moment 0.78

Boman Index0.08

Instability Index38.66

Aliphatic Index 104.12

Aromaticity 0.0608

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6467.46

LogP -61.94

H-bond Donors 226.0

H-bond Acceptors 218.0

Rotatable Bonds 524.0

Heavy Atoms 1125.0

Ring Count 21.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131406 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyCathelicidin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria