Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2564H3994N646O746S20

DescriptionStandard

        MHTIMVQVLWGCFLLWNLNMASSQTIYPGIKARVTQRALDYGIQAGMETIEQMIMDKSIPDLKGSESLEFLKVDYVNYNFSNIKIKAFSFPNTSLTFAPGVGIKVLTNHGTANVSTDWEVKSPLFQDAGGADLFLSGAFFTGILILSRNDFGHPILRLQDCQAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPMITNEVEALNGNLSMLEVLTKINNYTLLDYSLIDVPEITENYIDLNLKGTFYPLDNLTDPPFSPVPFVLPERSDSMLYIGIAEYFFKSASFAHFAAGAFDVTLSTKEISNHFVQNSQGLGNVLSRIAEIYILSKPFMVRFMAKEPPKINLQKGNFTLDIPASIMMLTQPENSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESSRSNIEVLRFENILSSLLHFGVLPLANAKLQQGFPLPNPHKISFVNSDIEVLEGLLLVSTDLKYEQNLKQQPNVHSWEDLNLINGYWSGKSAP
    

Molecular Weight56446.32 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-13.60

Net Charge (pH 7.4) -14.50

Charge Density (pH 7.0) -0.0268

GRAVY Index0.09

Hydrophobic Moment 0.68

Boman Index0.16

Instability Index34.33

Aliphatic Index 100.95

Aromaticity 0.0986

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48610.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048638 VERIFIED: NO

Provenance & Taxonomy

OrganismOrycteropus afer afer [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria