Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC99H155N25O35S4

DescriptionStandard

        GIVDQCCTSICTLYQLENYCN
    

Molecular Weight2383.70 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.28

Net Charge (pH 7.4) -2.54

Charge Density (pH 7.0) -0.1085

GRAVY Index0.22

Hydrophobic Moment 0.41

Boman Index0.14

Instability Index21.74

Aliphatic Index 88.10

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 993.43

LogP -11.44

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 76.0

Heavy Atoms 163.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128645 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla chinchilla [Animal]

FamilyInsulin

Tax ID10152

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0270710 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla chinchilla [Animal]

FamilyInsulin

Tax ID10152

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour