Peptide Database

Peptide NameHepcidin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC390H608N108O121S13

DescriptionStandard

        MKTLTVAVAVAVVLAFIWMQESAATFHGAQQPEEAVSNEDPAADPQETPVDSWMMPSNRQKRGMKCKFCCNCCNLNGCGVCCDF
    

Molecular Weight9162.50 Da

Isoelectric Point (pI)4.83

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.88

Charge Density (pH 7.0) -0.0414

GRAVY Index-0.04

Hydrophobic Moment 0.43

Boman Index0.07

Instability Index51.53

Aliphatic Index 58.10

Aromaticity 0.0714

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3651.25

LogP -40.62

H-bond Donors 128.0

H-bond Acceptors 132.0

Rotatable Bonds 295.0

Heavy Atoms 632.0

Ring Count 14.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055820 VERIFIED: YES

Provenance & Taxonomy

OrganismScophthalmus maximus [Animal]

FamilyHepcidin

Tax ID52904

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal