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MYP_158926
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Basic Information
Act Beta-defensin 2 (18-40)[C12I,G14p,P15G,C-del]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C112H186N40O27S2
Standard
Sequence
RCPGRTRQIGTIFPGRIKCRSW
Physicochemical Analysis
2589.06 Da
11.83
5.74
5.51
0.2609
-0.73
0.42
-0.31
48.06
53.18
0.0909
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1111.93
-12.08
44.0
35.0
83.0
181.0
5.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0303069 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655[LC = 4 microM]
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0304886 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans ATCC 18804
20 μM
MFC
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0322409 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
Acetylation
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0422202 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Hemolytic
Human erythrocytes (80% Hemolysis at 3 microM, Human erythrocytes (20% Hemolysis at 3 microM
3 μM
Hemolysis
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
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