Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC865H1367N239O234S8

DescriptionStandard

        EPMLLLAITEVMANSAAFAYFTAGALRRNISSNMLPRKFPLQLRTKSLGVFSPQLQEHYPDQAMELQLWARRQPLLSCHPDALHGTLFGSAEAFVVLPNGTRVPAFLLNIDANVTGKPTITGNRLRGTVKLTGHAPCPGTGAQGLPLPQVKRLENLLKFGLWLFGVPWANSECCP
    

Molecular Weight19115.09 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.16

Net Charge (pH 7.4) 5.70

Charge Density (pH 7.0) 0.0352

GRAVY Index0.03

Hydrophobic Moment 0.61

Boman Index0.12

Instability Index56.02

Aliphatic Index 93.71

Aromaticity 0.0800

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7453.65

LogP -77.37

H-bond Donors 255.0

H-bond Acceptors 252.0

Rotatable Bonds 608.0

Heavy Atoms 1346.0

Ring Count 37.0

Amide Bonds 191.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165273 VERIFIED: NO

Provenance & Taxonomy

OrganismEurystomus gularis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria