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MYP_158833
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Basic Information
Brevinin CTcu5 [L1W]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C108H177N29O24S2
Standard
Sequence
WIAGLAANFLPQILCKIARKC
Physicochemical Analysis
2329.87 Da
9.50
2.74
2.50
0.1304
0.84
0.74
0.28
25.84
130.48
0.0952
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
852.44
-3.92
31.0
29.0
75.0
163.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015178 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus coagulans ATCC 7050
12.5 μg/mL
MIC
PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0015756 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 39
PaperPubMed PMID: 25997127 PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0016509 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human epidermoid carcinoma A431[50-60% Cytotoxicity >100 microg/ml]
PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0078067 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
50 μg/mL
MIC
PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0197597 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25997127 PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
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