Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2399H3819N623O668S18

DescriptionStandard

        MAREPDSVLRWAALLVLATLGTAVMAATNPGVVARITQKGLDYACQQGVAVLQKELEKIKIPDFSGSFKIKHLGKGHYSFYSMVVRGFQLPSSQIRLVPNKGLDVSIINANMKISGKWKARKKFIKVKGNFDLSVTGISISAGLELGFDPASGLPTATCSSCSSHIDSVRVHISGGKIGWLIQLFHKKIESSIRNTMTSKICQIVTSSVSSKLQSYLKTLRVTTKIDKVAGINYSLVAPPTATADNLDGQLKGEFFSVAHPGPFPFTSPALAFPNDHDRMVYLGISDYFFNTAGFVYQQAGVLHLTITDDMIPKKSKFRLTTTFLGTLIPEVAKMFPNMMVQLNISASSPPHLTVLPTGLIFTPALEVQAFAVLPNSSLASLFVLHLSTNASMEVSATADRLVGKLSMDRLLLELKHSDIGPFSVVVLQAIMNYVLSTTVIPRINEWLMKGFPLPLPANIQLFNLVLQSHQNFLLFGADVHYS
    

Molecular Weight52653.93 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)15.61

Net Charge (pH 7.4) 14.58

Charge Density (pH 7.0) 0.0323

GRAVY Index0.23

Hydrophobic Moment 0.68

Boman Index0.17

Instability Index33.21

Aliphatic Index 102.73

Aromaticity 0.0849

Extinction Coeff. Reduced 36900.00

Extinction Coeff. Oxidized 37150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216997 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria