MYP_158786
Panitide L2
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Standard
28 amino acids
C134H218N40O38S6
Standard
QLPICGETCVLGRCYTPNCRCQYPICVR
3189.80 Da
8.34
1.70
1.41
0.0608
0.10
0.52
-0.01
3.40
76.43
0.0714
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1255.84
-12.94
49.0
46.0
97.0
218.0
5.0
30.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0065437
VERIFIED: YES
Provenance & Taxonomy
Steinchisma laxum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0203757
VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial
Antibacterial
Cytotoxic
Anti-Gram-negative
Escherichia coli
RECORD: Rec_0266578
VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial
Cytotoxic
HeLa cells