Peptide Database

Peptide NameFungal defensin plectasin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC452H674N120O136S9

DescriptionStandard

        MQFTTILSIGITVFGLLNTGAFAAPQPVPEAYAVSDPEAHPDDFAGMDANQLQKRGFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY
    

Molecular Weight10253.49 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-3.29

Net Charge (pH 7.4) -3.77

Charge Density (pH 7.0) -0.0346

GRAVY Index-0.27

Hydrophobic Moment 0.39

Boman Index0.10

Instability Index27.15

Aliphatic Index 54.53

Aromaticity 0.1158

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4049.17

LogP -42.25

H-bond Donors 139.0

H-bond Acceptors 145.0

Rotatable Bonds 327.0

Heavy Atoms 717.0

Ring Count 21.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075078 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudoplectania nigrella [other]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-positive Toxin Non-hemolytic

TargetS. pneumoniae (Gram-positive)