Peptide Database

Peptide NameBradykinin-potentiating peptide BmKbpp (Bpp BmK3) (Non-disulfide-bridged peptide 2.2) (NDBP-2.2) (Non-disulfide-bridged peptide 3.3) (NDBP-3.3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Enzyme modulation ▸ Enzyme inhibition ▸ Metalloenzyme inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC381H627N105O99S2

DescriptionStandard

        MNKKTLLVIFFVTMLIVDEVNSFRFGSFLKKVWKSKLAKKLRSKGKQLLKDYANKVLNGPEEEAAAPAERRR
    

Molecular Weight8326.83 Da

Isoelectric Point (pI)10.34

Net Charge (pH 7.0)9.50

Net Charge (pH 7.4) 9.26

Charge Density (pH 7.0) 0.1320

GRAVY Index-0.35

Hydrophobic Moment 0.76

Boman Index-0.12

Instability Index48.55

Aliphatic Index 92.08

Aromaticity 0.0972

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3367.53

LogP -25.68

H-bond Donors 118.0

H-bond Acceptors 111.0

Rotatable Bonds 293.0

Heavy Atoms 587.0

Ring Count 10.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017572 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Protease inhibitor Metalloenzyme inhibitor Metalloprotease inhibitor Toxin Enzyme inhibitory Non-hemolytic

TargetGram-negative and Gram-positive bacteria