Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC551H873N145O172S4

DescriptionStandard

        PNLNGYEKFGLGNVKYNISSIHVTDVEFPSASISLIPGTGIKMVIENASLAIDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTSLDNTGHTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12408.95 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)1.13

Net Charge (pH 7.4) 0.93

Charge Density (pH 7.0) 0.0099

GRAVY Index-0.01

Hydrophobic Moment 0.48

Boman Index0.12

Instability Index22.95

Aliphatic Index 89.74

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5107.24

LogP -58.40

H-bond Donors 182.0

H-bond Acceptors 179.0

Rotatable Bonds 412.0

Heavy Atoms 872.0

Ring Count 17.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257866 VERIFIED: NO

Provenance & Taxonomy

OrganismPodargus strigoides (Tawny frogmouth) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria