Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC360H560N102O105S3

DescriptionStandard

        QHWSYGLSPGGKRELDGLSETLGNQIVGGFPHVETPCRVLGCAVESPFPKIYRMKGFLDAVTDRENGPRTYKK
    

Molecular Weight8093.11 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)1.92

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.0264

GRAVY Index-0.59

Hydrophobic Moment 0.64

Boman Index-0.05

Instability Index24.73

Aliphatic Index 65.34

Aromaticity 0.0959

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3311.82

LogP -33.33

H-bond Donors 116.0

H-bond Acceptors 112.0

Rotatable Bonds 262.0

Heavy Atoms 570.0

Ring Count 16.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136385 VERIFIED: YES

Provenance & Taxonomy

OrganismMorone saxatilis [Animal]

FamilyProgonadoliberin

Tax ID34816

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour