Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC545H867N163O172S11

DescriptionStandard

        MKLLTTICRLKLEKMYSKTNTSSTISEKAHGTEKISTARSEGHHITFSRWKACTAIGGRCKNQCDDSEFRISYCARPTTRCCVTECDPMDPNNWIPKDSVGTQEWYPKDSRH
    

Molecular Weight12807.42 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)4.78

Net Charge (pH 7.4) 4.21

Charge Density (pH 7.0) 0.0427

GRAVY Index-0.83

Hydrophobic Moment 0.60

Boman Index-0.20

Instability Index53.73

Aliphatic Index 47.95

Aromaticity 0.0714

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5456.61

LogP -65.92

H-bond Donors 203.0

H-bond Acceptors 192.0

Rotatable Bonds 426.0

Heavy Atoms 891.0

Ring Count 20.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031132 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0101854 VERIFIED: NO