Peptide Database

Peptide NamePIP-18

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC96H138N24O27

DescriptionStandard

        VDIHVWDGVVDIHVWDGV
    

Molecular Weight2060.27 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-4.09

Net Charge (pH 7.4) -4.40

Charge Density (pH 7.0) -0.2271

GRAVY Index0.62

Hydrophobic Moment 0.34

Boman Index0.41

Instability Index6.46

Aliphatic Index 140.00

Aromaticity 0.1111

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 796.16

LogP -2.79

H-bond Donors 27.0

H-bond Acceptors 25.0

Rotatable Bonds 61.0

Heavy Atoms 147.0

Ring Count 6.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029555 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cytotoxic

TargetHuman erythrocytes

Activity100 μM

MethodHemolysis

RECORD: Rec_0333832 VERIFIED: YES