Peptide Database

Peptide NameH-20

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC44H64N10O15

DescriptionStandard

        ISYGGADYK
    

Molecular Weight973.04 Da

Isoelectric Point (pI)5.83

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0269

GRAVY Index-0.59

Hydrophobic Moment 0.21

Boman Index0.10

Instability Index-5.70

Aliphatic Index 54.44

Aromaticity 0.2222

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 420.13

LogP -3.90

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 30.0

Heavy Atoms 69.0

Ring Count 2.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320293 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAnalgesic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Analgesic Receptor agonist Immunomodulatory

TargetPD-1; mouse pain models

Activity57 μM

MethodMST binding assay