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MYP_158510
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Basic Information
Islet amyloid polypeptide
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
36 amino acids
C162H259N45O53S3
Standard
Sequence
CGTATCETQRLANFLAPSSNKLGAIFSPTKMGSNTY
Physicochemical Analysis
3781.25 Da
8.86
1.74
1.50
0.0483
-0.18
0.44
0.06
37.91
54.44
0.0833
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1590.14
-22.27
57.0
58.0
121.0
263.0
5.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0106458 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Calcitonin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Calcium-regulatory peptide
Evidence URLhttps://www.uniprot.org/uniprotkb/IAPP_BOVIN/entry
RECORD: Rec_0135618 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 30.6%, E 0.0%, T 36.1%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0165540 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Islet amyloid polypeptide
9913
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Islet amyloid polypeptide (Bos taurus): PMID 19390049 PMID19390049 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19390049/
RECORD: Rec_0174928 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
RECORD: Rec_0376298 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/