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MYP_158505
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Basic Information
KEY (S-S)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
13 amino acids
C66H92N16O17S2
Standard
Sequence
ACFPWGKEYCGGK
Physicochemical Analysis
1445.66 Da
8.07
0.78
0.55
0.0597
-0.52
0.20
0.10
44.08
7.69
0.2308
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
529.09
-3.47
20.0
20.0
43.0
101.0
5.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0298397 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Hepatitis C virus(HCV):inhibition of polymerase activity
150 μM
IC50
PaperPubMed PMID: 12951030 PMID12951030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12951030/
RECORD: Rec_0314562 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
2-10
Bio-Activity Profile
Antimicrobial Antiviral
Hepatitis C virus(HCV):inhibition of polymerase activity
22 μM
IC50
PaperPubMed PMID: 12951030 PMID12951030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12951030/
RECORD: Rec_0321541 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Library-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Hepatitis C virus (RdRp); Huh7
150 μM
Surface plasmon resonance
PaperIdentification of constrained peptides that bind to and preferentially inhibit the activity of the hepatitis C viral RNA-dependent RNA polymerase. | Amin A, Zaccardi J, Mullen S, Olland S, Orlowski M, Feld B, Labonte P, Mak P. | Virology. 2003 | PMID:12951030 PMID12951030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12951030/
RECORD: Rec_0343340 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 12951030 PMID12951030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12951030/
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