Peptide Database

Peptide NameEtelcalcetide

Function Ontology

Calcimimetic Anti-hyperparathyroidism

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC36H70N20O9S2

DescriptionStandard

        CCARRRAR
    

Molecular Weight991.20 Da

Isoelectric Point (pI)11.53

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.51

Charge Density (pH 7.0) 0.4675

GRAVY Index-1.18

Hydrophobic Moment 0.54

Boman Index-1.04

Instability Index151.95

Aliphatic Index 25.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 514.62

LogP -7.26

H-bond Donors 23.0

H-bond Acceptors 15.0

Rotatable Bonds 33.0

Heavy Atoms 67.0

Ring Count 0.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133487 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCalcimimetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Calcimimetic Anti-hyperparathyroidism

TargetCalcium-sensing receptor

Half-LifeClinical/Human: 3-4 d