Peptide Database

Peptide NameD-Kalata B1

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC121H193N37O42S6

DescriptionStandard

        CGETCVGGTCNTPGCTCSWPVCTRNGLNPV
    

Molecular Weight3030.44 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0099

GRAVY Index0.03

Hydrophobic Moment 0.35

Boman Index0.12

Instability Index32.98

Aliphatic Index 42.00

Aromaticity 0.0333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1246.49

LogP -19.90

H-bond Donors 48.0

H-bond Acceptors 48.0

Rotatable Bonds 88.0

Heavy Atoms 206.0

Ring Count 5.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0026482 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclotide

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralityall-D amino-acid peptide [D]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Antiviral Anti-HIV

TargetHuman erythrocytes

Activity77 μM

MethodIC50

RECORD: Rec_0109725 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclotide

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0122744 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0313590 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclotide

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

RECORD: Rec_0424016 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclotide

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic