Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length391 amino acids

Chemical FormulaC1954H3068N520O548S14

DescriptionStandard

        SRLDLRSFHLPYSRISLVPNVGLQVSIANAFADVDGNWRVKIHFLRDHGSFEVSVENVYIKINLKLGNDASGKPTVDTSHCSTRISKVRVHFSGRLGWLYNLFHSAIESRFRKILESKVCDIVAKSVHNDLQPYVQTLPVTTKIDAIAGVDYSLVEPPAATAQSLDVAMKGECYSLAQRSAVPFAPLPLALPSDHDRMVYFGASSYFFNTASFAYHEAGALVFEITDSMVSSIPQELGFFCHCPYHLPAPLQLEQMYPDMKMKLKLSAPSAPFLSIGPGGLSLKPVVDIQAYAILPNSSLAPLFLINLVSNVSAVINVVSGHIIGNLNVGRMKLSLKHSDVGTFQMRTLQSIMNIYASSILLPRINDRLGQGFPLPLPDRIQLSNIVVQFH
    

Molecular Weight43061.33 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)4.65

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.0119

GRAVY Index0.16

Hydrophobic Moment 0.69

Boman Index0.14

Instability Index41.61

Aliphatic Index 103.45

Aromaticity 0.0895

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039837 VERIFIED: NO

Provenance & Taxonomy

OrganismRostratula benghalensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria