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MYP_158352
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
23 amino acids
C132H187N33O27
Standard
Sequence
VFHLLGKIIHHVGNFVYGFSHVF
Physicochemical Analysis
2668.10 Da
8.59
1.08
0.66
0.0470
0.92
0.61
0.50
-13.34
118.26
0.2174
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
927.81
-2.45
32.0
32.0
82.0
192.0
9.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0219184 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25922
16 μg/mL
MIC
PaperClavanins, alpha-helical antimicrobial peptides from tunicate hemocytes.
RECORD: Rec_0258257 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Clavanin
7725
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperFEBS Lett. 1997 Jan 3;400(2):158-62. | http://www.ncbi.nlm.nih.gov/pubmed/9001389 PMID9001389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9001389/
RECORD: Rec_0302643 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Clavanin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID9001389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9001389/
RECORD: Rec_0344721 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0371574 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperLee I.H., Zhao C., Cho Y., Harwig S.S.L., Cooper E.L., Lehrer R.I.;. "Clavanins, alpha-helical antimicrobial peptides from tunicate hemocytes."; FEBS Lett. 400:158-162. Evidence URLhttps://www.uniprot.org/uniprotkb/CLVC_STYCL/entry
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