Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC395H648N110O116S11

DescriptionStandard

        MKTLTAAVTVAIVVTIMCILRSSAVPVVEEQLLVELMNTDNPAAEPEEISVNSWKMLHNGRQKRGIFCGTCCNGKVCWRCCYA
    

Molecular Weight9146.75 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.53

Net Charge (pH 7.4) 0.14

Charge Density (pH 7.0) 0.0064

GRAVY Index0.30

Hydrophobic Moment 0.47

Boman Index0.12

Instability Index51.57

Aliphatic Index 95.06

Aromaticity 0.0482

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3620.35

LogP -35.08

H-bond Donors 132.0

H-bond Acceptors 129.0

Rotatable Bonds 301.0

Heavy Atoms 632.0

Ring Count 10.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159550 VERIFIED: NO

Provenance & Taxonomy

OrganismPundamilia nyererei [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal