Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC459H720N124O137S14

DescriptionStandard

        LPDGDFMIQGCPECKLKENKYFSKLGAPIYQCMGCCFSSAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNARVENHTECHCSTCYYHKS
    

Molecular Weight10616.29 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)4.92

Net Charge (pH 7.4) 4.39

Charge Density (pH 7.0) 0.0513

GRAVY Index-0.30

Hydrophobic Moment 0.53

Boman Index-0.01

Instability Index53.30

Aliphatic Index 48.85

Aromaticity 0.0938

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4169.36

LogP -46.21

H-bond Donors 153.0

H-bond Acceptors 159.0

Rotatable Bonds 345.0

Heavy Atoms 734.0

Ring Count 18.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198438 VERIFIED: YES

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyGlycoprotein hormones

Tax ID10036

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min