Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 18.3

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC156H255N43O55S7

DescriptionStandard

        GEGPKSDCKPDLCEAACKDLGKPMDFCKDGTCKCKD
    

Molecular Weight3837.40 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0359

GRAVY Index-0.90

Hydrophobic Moment 0.49

Boman Index-0.23

Instability Index4.64

Aliphatic Index 27.22

Aromaticity 0.0278

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1576.45

LogP -19.03

H-bond Donors 57.0

H-bond Acceptors 61.0

Rotatable Bonds 131.0

Heavy Atoms 261.0

Ring Count 4.0

Amide Bonds 35.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0222976 VERIFIED: NO

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-27; 13-32; 17-34

Bio-Activity Profile

Function

Toxin

TargetKv1