Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2335H3657N677O713S14

DescriptionStandard

        MIAPIGDWLGSGPSPEQIVRERHAVMLAERRAEQEREEKHREEERERNRVFAKSCLRGEGCNDAGDQREPHTNFADMAFFQAMPASDPVTDSDTPQHAQTARKKKPEDIPKPKKRSALYRWWNGNHEEMDYQAAVAAASAAARAQTATAGASLLELISGRALTYGTWAVRGAVAGPGAPVAGLLVGMMPGRLNDGEQDFIDRMRLEQMHEAPSRVRYTWEKDSRGNPVPHGWHTPPGRDSVRVRKMEYDTSAQAYTFTTEEDPHITIIWTPDRTVEEKPWNTGNQARPVLPKPVIVDPLPDNTGITATTSPAPEEKHFADYILILPFPDLPPIYIYLSKPPVEFLEVELYSDFKRRSRQGVYEADHMPSAAAVKAYLRREYPYLKETEIQEFSLQVAAIVVPKDVHQKISETYGGRNTLTQIDLDSQNLRAAADRNLDTIKPSLKKQGATEEQIETARTKMHALNGQQGLYK
    

Molecular Weight53070.04 Da

Isoelectric Point (pI)6.06

Net Charge (pH 7.0)-6.28

Net Charge (pH 7.4) -7.33

Charge Density (pH 7.0) -0.0133

GRAVY Index-0.72

Hydrophobic Moment 0.57

Boman Index-0.12

Instability Index50.74

Aliphatic Index 68.31

Aromaticity 0.0742

Extinction Coeff. Reduced 67840.00

Extinction Coeff. Oxidized 67965.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046330 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter sp. 50588862 [Bacterium]

FamilyPyocin/Colicin

Tax ID1736698

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli