Peptide Database

Peptide Namehuman GIP(3-30)NH2

Function Ontology

Hormonal / Endocrine ▸ Hormonal activity

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC150H225N37O45S

DescriptionStandard

        EGTFISDYSIAMDKIHQQDFVNWLLAQK
    

Molecular Weight3298.68 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.08

Net Charge (pH 7.4) -2.30

Charge Density (pH 7.0) -0.0741

GRAVY Index-0.27

Hydrophobic Moment 0.35

Boman Index0.09

Instability Index21.13

Aliphatic Index 87.14

Aromaticity 0.1429

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1348.01

LogP -10.49

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 110.0

Heavy Atoms 233.0

Ring Count 6.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401107 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-Termamidated

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Receptor antagonist Antidiabetic Hormonal activity

TargetGIP receptor (Human)

Activity2.3 nM

MethodKi