Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC376H621N103O98S8

DescriptionStandard

        MRSLLLALAILVLLSSVPPVKSGPNAYINKFFNTCWRMKGSCRRVCSSKEIYHLLCDHTTVCCINKKELPVLVGK
    

Molecular Weight8409.10 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.61

Net Charge (pH 7.4) 7.19

Charge Density (pH 7.0) 0.1015

GRAVY Index0.32

Hydrophobic Moment 0.74

Boman Index0.09

Instability Index57.58

Aliphatic Index 109.07

Aromaticity 0.0667

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3211.47

LogP -26.59

H-bond Donors 119.0

H-bond Acceptors 116.0

Rotatable Bonds 278.0

Heavy Atoms 585.0

Ring Count 12.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153532 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9365

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic