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MYP_158141
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Basic Information
Chicken CATH-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C149H247N51O32
Standard
Sequence
RFGRFLRKIRRFRPKVTITIQGSARFG
Physicochemical Analysis
3264.88 Da
12.00
8.76
8.55
0.3244
-0.49
1.06
-0.32
35.68
72.22
0.1481
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1400.25
-12.65
54.0
41.0
111.0
232.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0330455 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Cathelicidin
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes ATCC 19115
1.33 μM
MIC
PaperCMAP27, a novel chicken cathelicidin-like antimicrobial protein
RECORD: Rec_0348152 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Cathelicidin
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922 or O157:H7 or PCN033 or RS218
0.66-10 μM
MIC
PaperCMAP27, a novel chicken cathelicidin-like antimicrobial protein
RECORD: Rec_0363328 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Cathelicidin
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. typhimurium ATCC 14028 or 700408
0.66-1.33 μM
MIC
PaperCMAP27, a novel chicken cathelicidin-like antimicrobial protein
RECORD: Rec_0395603 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
Defensin
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID15963828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15963828/
RECORD: Rec_0396588 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 29.6%, E 14.8%, T 22.2%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative Immunomodulatory Antibiofilm
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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