Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length143 amino acids

Chemical FormulaC696H1149N217O189S5

DescriptionStandard

        RSPRRLRPSTARSPQMQELYPDRPMELRVWARRQPLLSCRPDGLRLALHGTAETVVLLPNGTRAPAFLLHLEANVTGKPVLTANRIGGPCWAQGVPVGLKGSLPDSRGPRIPQVQNLENLLSFGLRLLGLPLLNRECRPTAPP
    

Molecular Weight15741.23 Da

Isoelectric Point (pI)11.47

Net Charge (pH 7.0)10.92

Net Charge (pH 7.4) 10.56

Charge Density (pH 7.0) 0.0764

GRAVY Index-0.31

Hydrophobic Moment 0.59

Boman Index-0.07

Instability Index58.76

Aliphatic Index 96.85

Aromaticity 0.0350

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6439.92

LogP -64.70

H-bond Donors 224.0

H-bond Acceptors 207.0

Rotatable Bonds 499.0

Heavy Atoms 1107.0

Ring Count 28.0

Amide Bonds 154.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113644 VERIFIED: NO

Provenance & Taxonomy

OrganismCrypturellus undulatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria