Peptide Database

Peptide NameSLAY-screened peptide P417

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC105H158N26O30S

DescriptionStandard

        RPIIPYSAHSYLCVTTYNPT
    

Molecular Weight2296.60 Da

Isoelectric Point (pI)8.18

Net Charge (pH 7.0)0.83

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0417

GRAVY Index-0.12

Hydrophobic Moment 0.29

Boman Index0.14

Instability Index3.99

Aliphatic Index 78.00

Aromaticity 0.1500

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 885.36

LogP -8.05

H-bond Donors 32.0

H-bond Acceptors 33.0

Rotatable Bonds 63.0

Heavy Atoms 162.0

Ring Count 7.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109882 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/