Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1187 amino acids

Chemical FormulaC5852H9093N1649O1788S36

DescriptionStandard

        MDNWLALFDGQTRYFLDIFDSSVKPDVLRFYGREALSEPFSWDIEFTTLQANIPPEEVLMKYASFRMRSGKSVHGMVTRLEWLSTSKDQSHCRLTISSRLALLGYTRQCVVYQNQSVPEVVEQVLRKHGLEGPDFEFRLERTYPPREIITQWRETDLQFIQRILSEVGIYWRTEMDDVRGLDTYILADSQLNYQFDVQLPYSEPSGLFDSVAESVWDVRTWHNIATGTVTTRDYNYRTATMPMNAAVSVRNDVVTTGEHYRYAAPYREAGDDASPEPETESGAFWARLHHERELNRSARIHLFSNAAHLTPGQVLEPQGDVITALQEGVILTLVTFRGARDSRLHVSVWGQPYTERYCFRPAEIPRPVIAGTLPARIESREKNDTYAHLDEQGRYRVKQDFDREGTEPGYGYLWLRMAKPYAGETLGWHTPLIDGTEVAIAYSNGDIDLPYIACALHDSEHPDLVNRDNHTRNILRTPANSKLRMEDKRGEEHIKLATEYGKTQLNNGHLVNSKGQLRGKGTELRTDEWGVLRAGKGLFVAADVQAKAQGDALDMDAALKEIDRLNQQLQQLEMAAEKALALKGDVDSQIQMFEQRLKPLNEAVLFSAPEGMALTSGEDMQLAAGRNLALNAGEDFSAGVMGNATALTGEKLGLFARTGQLSLKSGEGPIDVQAQNASMRLFAEKKLTLSSASDISFAGKKRITLIGGGSYLKLEAGKVEYGTTASYVRKVKRTMAASASAKPPEALSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHQHEHADDEVVQHAQSAKKRKPDAGGAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKAITGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSEHNQYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIKPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKTARDEPGVATGKGETLSGSEKWLEAASSGLGAPVPAQVADKLRGKPFRNFDHFREEFWLAVAECPELMSQFKRVNQMEIRDGNAPFSIVPEQVGGRKRFEIHHIERIIDSGAVYDFENMRVNTVRNHINLHSKKNR
    

Molecular Weight132310.12 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-29.73

Net Charge (pH 7.4) -31.93

Charge Density (pH 7.0) -0.0250

GRAVY Index-0.49

Hydrophobic Moment 0.74

Boman Index-0.04

Instability Index35.27

Aliphatic Index 74.90

Aromaticity 0.0868

Extinction Coeff. Reduced 176590.00

Extinction Coeff. Oxidized 177090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109798 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia sp. E1130 [Bacterium]

FamilyVgrG protein family

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli