Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length342 amino acids

Chemical FormulaC1721H2684N454O486S7

DescriptionStandard

        RLRLRDFHLPYSRITPVSNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFDLKVENVYIKIILRLGSDATGKPTISTSDCSAHISNVRVLFSGKFGWLYNLFHSSIESRFRKILEDKVCDSVAKSVHNELQTYIQTLPVTARIDAKTGIDYSLVAAPRATAQSLDADLKGEFYSLAHRSTVPFSPPPLAFPSDHDRMVYFGASSYFFNTASLAYHKAGALVFEITEAMIPKDVGFSLNTSVFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIAPGGISFQPIVDVQAYAILPNSSVAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQV
    

Molecular Weight37734.93 Da

Isoelectric Point (pI)9.11

Net Charge (pH 7.0)5.46

Net Charge (pH 7.4) 4.76

Charge Density (pH 7.0) 0.0160

GRAVY Index0.14

Hydrophobic Moment 0.69

Boman Index0.12

Instability Index38.13

Aliphatic Index 97.78

Aromaticity 0.1082

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 27515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212767 VERIFIED: NO

Provenance & Taxonomy

OrganismMelanocharis versteri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria