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MYP_157986
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Basic Information
NPP
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Standard
80 amino acids
C357H552N112O117S5
Standard
Sequence
WCLESSQCQDLSTESNLLACIRACKPDLSAETPVFPGNGDAQPLTENPRKYVMGHFRWDRFGRRNGSSSGGGGGGGGAGQ
Physicochemical Analysis
8445.21 Da
6.75
-0.18
-0.51
-0.0022
-0.68
0.73
-0.07
65.63
47.62
0.0750
12490.00
12740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3687.85
-50.80
131.0
123.0
274.0
591.0
14.0
87.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066224 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
NPP
9823
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
61:Phenylalanine amide; 65:N-linked (GlcNAc...) asparagine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for NPP (Sus scrofa): PMID 3753882 PMID3753882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3753882/
RECORD: Rec_0274391 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0282981 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
POMC
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Phe61 Amidation
Bio-Activity Profile
Hormone precursor Neuropeptide precursor