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MYP_157927
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Basic Information
Ts1
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Membrane / Ion-channel modulation ▸ Ion channel inhibition
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
61 amino acids
C303H453N83O84S9
Standard
Sequence
KEGYLMDHEGCKLSCFIRPSGYCGRECGIKKGSSGYCAWPACYCYGLPNWVKVWDRATNKC
Physicochemical Analysis
6890.93 Da
8.67
3.77
3.37
0.0618
-0.44
0.69
-0.02
29.47
46.39
0.1475
23950.00
24450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2675.80
-24.82
103.0
98.0
219.0
479.0
16.0
62.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037244 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
P. verrucosum
PMID28634472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28634472/
RECORD: Rec_0072905 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Sodium channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
11-61; 15-37; 23-42; 27-44
Bio-Activity Profile
Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense
PaperPDB 1B7D structural record; X-ray; 1.73 A; chain A; residues 1-61
RECORD: Rec_0077082 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
A. terreus
PMID28634472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28634472/
RECORD: Rec_0242693 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
P. corylophilum
PMID28634472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28634472/
RECORD: Rec_0247762 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
ed the fungal growth of A. nidulans
2.1 μM
MIC
PaperAntifungal Activity against Filamentous Fungi of Ts1, a Multifunctional Toxin from Tityus serrulatus Scorpion Venom
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