Peptide Database

Peptide NameEppin (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)

Function Ontology

Antimicrobial

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length134 amino acids

Chemical FormulaC680H1058N200O196S16

DescriptionStandard

        MKFSRFVSILVLFGLLTKVQGPSLTDFLFPRRCPRFREECEHRERDLCTRDRDCQKREKCCIFSCGKKCLNPQQDICSLPKDSGYCMAYFPRWWYNKKNGTCQLFIYGGCQGNNNNFQSQSICQNACEKKSNST
    

Molecular Weight15683.94 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)9.46

Net Charge (pH 7.4) 8.95

Charge Density (pH 7.0) 0.0706

GRAVY Index-0.66

Hydrophobic Moment 0.55

Boman Index-0.19

Instability Index54.16

Aliphatic Index 51.64

Aromaticity 0.1194

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6515.85

LogP -71.73

H-bond Donors 239.0

H-bond Acceptors 223.0

Rotatable Bonds 526.0

Heavy Atoms 1092.0

Ring Count 25.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401566 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Protease inhibitor Serine protease inhibitor Enzyme inhibitory Non-hemolytic