Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC125H204N32O38S6

DescriptionStandard

        PCGESCVFIPCISSIVGCSCKSKVCYKN
    

Molecular Weight2955.54 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.75

Charge Density (pH 7.0) 0.0678

GRAVY Index0.57

Hydrophobic Moment 0.37

Boman Index0.17

Instability Index25.79

Aliphatic Index 72.86

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1106.07

LogP -13.35

H-bond Donors 45.0

H-bond Acceptors 46.0

Rotatable Bonds 95.0

Heavy Atoms 201.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336947 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)