Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC315H536N78O83S3

DescriptionStandard

        MMKVKKLGLFSLLLIAGTMASLVVSNGSSVATVITSVGVFFGVGIISSGVAAAILAVLKKQGKAKAAAF
    

Molecular Weight6840.29 Da

Isoelectric Point (pI)10.78

Net Charge (pH 7.0)6.49

Net Charge (pH 7.4) 6.27

Charge Density (pH 7.0) 0.0941

GRAVY Index1.24

Hydrophobic Moment 0.44

Boman Index0.43

Instability Index10.59

Aliphatic Index 131.45

Aromaticity 0.0580

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2532.97

LogP -21.85

H-bond Donors 90.0

H-bond Acceptors 93.0

Rotatable Bonds 234.0

Heavy Atoms 479.0

Ring Count 4.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324841 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus pumilus [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic

MethodQualitative functional evidence