Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC422H653N111O125S10

DescriptionStandard

        MKTFSVAVVVAVLLAFVYLQESSAFPPNKLDDLEVPAIDDAAAAAYEEISDDSWKTPYTNRHKRSPARCRFCCGCCPGMIGCGTCCKF
    

Molecular Weight9602.02 Da

Isoelectric Point (pI)5.67

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -1.89

Charge Density (pH 7.0) -0.0168

GRAVY Index0.11

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index57.72

Aliphatic Index 71.02

Aromaticity 0.1023

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3729.71

LogP -36.49

H-bond Donors 136.0

H-bond Acceptors 135.0

Rotatable Bonds 303.0

Heavy Atoms 668.0

Ring Count 17.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028623 VERIFIED: NO

Provenance & Taxonomy

OrganismTetraodon nigroviridis [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence