Peptide Database

Peptide NameMacedovicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC84H137N21O28S4

DescriptionStandard

        ASSGWVCTLTIECGTLVCAC
    

Molecular Weight2017.37 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.49

Charge Density (pH 7.0) -0.0620

GRAVY Index1.26

Hydrophobic Moment 0.14

Boman Index0.43

Instability Index99.02

Aliphatic Index 97.50

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 770.46

LogP -9.20

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 61.0

Heavy Atoms 137.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262890 VERIFIED: YES

Provenance & Taxonomy

OrganismActinoplanes liguriensis [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)