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MYP_157817
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Basic Information
Angiotensin I-converting enzyme inhibitor WH
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
2 amino acids
C17H19N5O3
Standard
Sequence
WH
Physicochemical Analysis
341.36 Da
6.74
-0.15
-0.41
-0.0764
-2.05
0.48
0.20
123.40
0.00
0.5000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
136.89
0.57
5.0
4.0
7.0
25.0
3.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0102559 VERIFIED: YES
Provenance & Taxonomy
Undaria pinnatifida [Protist]
74381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Vasorelaxant ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
PaperAntihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats PMID15135150 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15135150/
RECORD: Rec_0127281 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
RECORD: Rec_0134312 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
RECORD: Rec_0145486 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic Alpha-glucosidase inhibitory
Alpha-glucosidase
17.03
IC50
PaperGu X., Gao T., Hou Y., Li D., Fu L.. Identification and characterization of two novel alpha-glucosidase inhibitory peptides from almond (armeniaca sibirica) oil manufacture residue. LWT, 134, 110215, 2020.
RECORD: Rec_0190220 VERIFIED: YES
Provenance & Taxonomy
Undaria pinnatifida [Protist]
ACE-inhibitory peptide
74381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
5.1 μM
IC50
PaperAntihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats PMID15135150 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15135150/
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