Peptide Database

Peptide Namebeta-Defensin, DEFB12

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC168H269N53O59S7

DescriptionStandard

        KSCTAIGGRCKNQCDDSEFRISYCARPTTHCCVTECDP
    

Molecular Weight4199.71 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.22

Net Charge (pH 7.4) -0.58

Charge Density (pH 7.0) -0.0057

GRAVY Index-0.59

Hydrophobic Moment 0.42

Boman Index-0.20

Instability Index63.93

Aliphatic Index 33.42

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1823.38

LogP -26.09

H-bond Donors 71.0

H-bond Acceptors 67.0

Rotatable Bonds 135.0

Heavy Atoms 287.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398066 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-31; 10-24; 14-32

Bio-Activity Profile

Function

Antimicrobial