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MYP_157768
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Basic Information
Orexin-B
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
28 amino acids
C125H213N43O35S
Standard
Sequence
RPGPPGLQGRLQRLLQASGNHAAGILTM
Physicochemical Analysis
2910.36 Da
12.00
2.85
2.59
0.1017
-0.29
0.60
0.01
59.14
94.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1249.85
-14.95
42.0
40.0
94.0
204.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054340 VERIFIED: NO
Provenance & Taxonomy
Canis familiaris [Animal]
Orexin
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator
RECORD: Rec_0130236 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Orexin
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Orexin-B (Canis lupus familiaris): PMID 11282968 PMID11282968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11282968/
RECORD: Rec_0166576 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
Orexin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator
RECORD: Rec_0203485 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0250180 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Orexin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Orexin-B (Sus scrofa): PMID 10754114 PMID10754114 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10754114/