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MYP_157763
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Basic Information
Ocellatin-3N
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C89H152N22O26
Standard
Sequence
GIFDVLKNLAKGVITSLAS
Physicochemical Analysis
1946.29 Da
8.59
0.76
0.55
0.0400
0.91
0.69
0.34
2.56
143.68
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.24
-6.81
27.0
27.0
66.0
137.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0289728 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis ATCC 12228
6.25 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
RECORD: Rec_0305812 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
antibiotic-resistant Klebsiella pneumoniae ATCC 49472 or ATCC BAA-2814
62.5 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
RECORD: Rec_0331137 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID36426386 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/36426386/
RECORD: Rec_0351411 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii ATCC 19606
6.25 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
RECORD: Rec_0382398 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028
62.5 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
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